Also, it has little effect on the nontoxic routes of elimination of acetaminophen and is itself quite nontoxic. The H 2-receptor antagonist cimetidine inhibits the cytochrome P-450 system, does not interfere with the administration or function of NAC, and therefore affords additive protection. An alternative or additive approach to therapy would be to inhibit the formation of the toxic metabolite by inhibiting the cytochrome P-450 system. Present treatment of acetaminophen overdose involves oral N-acetylcysteine (NAC), which enhances liver glutathione synthesis.

Garlic Cyanide poisoning smells like.Acetaminophen, a drug frequently taken in intentional and accidental overdose, causes liver toxicity when concentration of the cytochrome P-450-derived metabolite exceeds the metabolic capacity of available glutathione. Antidote for Heparin overdose? Protamine sulfate What is the treatment of choice in Iron overdose? Deferoxamine, deferasirox What are some common antidotes for Lead poisoning? EDTA, dimercaperol, succimer, penicillamine Mercury, arsenic gold Dimercaprol, Succimer What antidote is used to treat Methanol or Ethylene glycol toxicity? Fomepizole > ethanol, dialysis What is the treatment for Methemoglobinemia? Methylene blue, vitamin C What is the antidote for Opioid overdose? Naloxone What is the antidote for salicylate overdose? NaHCO3 (alkalinize urine), dialysis What is the antidote for acute TCA poisoning? NaHCO3 (plasma alkalinization) What is the antidote of choice for overdose of tPA/streptokinase/urokinase? Aminocaproic acid What is the antidote for Warfarin toxicity? Fresh frozen plasma (immediate), Vitamin K (Delayed effect) Arsenic poisoning smells like.

Antidote for acetaminophen toxicity